O’Driscoll, Caitriona M.: search on Z-Library

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1

Oligonucleotide conjugates – Candidates for gene silencing therapeutics

Gooding, Matt, Malhotra, Meenakshi, Evans, James C., Darcy, Raphael, O’Driscoll, Caitriona M.

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.74 MB

english, 2016

2

Food for thought: formulating away the food effect - a PEARRL review

O'Shea, Joseph P., Holm, René, O'Driscoll, Caitriona M., Griffin, Brendan T.

Journal:

Journal of Pharmacy and Pharmacology

Year:

2018

Language:

english

File:

PDF, 745 KB

english, 2018

3

Life in 3D is Never Flat: 3D Models to Optimise Drug Delivery

Fitzgerald, Kathleen A., Malhotra, Meenakshi, Curtin, Caroline M., O’ Brien, Fergal J., O’ Driscoll, Caitriona M.

Journal:

Journal of Controlled Release

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

4

A Retrospective Biopharmaceutical Analysis of >800 Approved Oral Drug Products: Are Drug Properties of Solid Dispersions and Lipid-Based Formulations Distinctive?

Bennett-Lenane, Harriet, O'Shea, Joseph P., O'Driscoll, Caitriona M., Griffin, Brendan T.

Journal:

Journal of Pharmaceutical Sciences

Year:

2020

File:

PDF, 1.93 MB

2020

5

A novel lipid-based solid dispersion for enhancing oral bioavailability of Lycopene – In vivo evaluation using a pig model

Faisal, Waleed, Ruane-O’Hora, Therese, O’Driscoll, Caitriona M., Griffin, Brendan T.

Journal:

International Journal of Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 834 KB

english, 2013

6

Anisamide-targeted cyclodextrin nanoparticles for siRNA delivery to prostate tumours in mice

Jianfeng Guo, Julien R. Ogier, Stephane Desgranges, Raphael Darcy, Caitriona O′Driscoll

Journal:

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

7

Antibody-Targeted Cyclodextrin-Based Nanoparticles for siRNA Delivery in the Treatment of Acute Myeloid Leukemia: Physicochemical Characteristics, in Vitro Mechanistic Studies, and ex Vivo Patient Derived Therapeutic Efficacy

Guo, Jianfeng, Russell, Eileen G., Darcy, Raphael, Cotter, Thomas G., McKenna, Sharon L., Cahill, Mary R., O’Driscoll, Caitriona M.

Journal:

Molecular Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 3.43 MB

english, 2017

8

Predicting budesonide performance in healthy subjects and patients with Crohn's disease using biorelevant in vitro dissolution testing and PBPK modeling

Effinger, Angela, O'Driscoll, Caitriona M., McAllister, Mark, Fotaki, Nikoletta

Journal:

European Journal of Pharmaceutical Sciences

Year:

2020

File:

PDF, 1.19 MB

2020

9

Lipid-based formulations for intestinal lymphatic delivery

Caitriona M. O’Driscoll

Journal:

European Journal of Pharmaceutical Sciences

Year:

2002

Language:

english

File:

PDF, 305 KB

english, 2002

10

Physicochemical, pharmacokinetic and pharmacodynamic analyses of amphiphilic cyclodextrin-based nanoparticles designed to enhance intestinal delivery of insulin

Presas, Elena, McCartney, Fiona, Sultan, Eric, Hunger, Corina, Nellen, Sabine, Alvarez, Clara V., Werner, Ulrich, Bazile, Didier, Brayden, David J., O'Driscoll, Caitriona M.

Journal:

Journal of Controlled Release

Year:

2018

Language:

english

File:

PDF, 1.48 MB

english, 2018

11

Mechanistic Studies on Nonviral Gene Delivery to the Intestine Usingin VitroDifferentiated Cell Culture Models and anin VivoRat Intestinal Loop

Sally-Ann Cryan, Caitriona M. O'Driscoll

Journal:

Pharmaceutical Research

Year:

2003

Language:

english

File:

PDF, 310 KB

english, 2003

12

Delivering RNAi therapeutics with non-viral technology: a promising strategy for prostate cancer?

Guo, Jianfeng, Evans, James C., O’Driscoll, Caitriona M.

Journal:

Trends in Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 809 KB

english, 2013

13

Differential nanotoxicological and neuroinflammatory liabilities of non-viral vectors for RNA interference in the central nervous system

Godinho, Bruno M.D.C., McCarthy, David J., Torres-Fuentes, Cristina, Beltrán, Caroll J., McCarthy, Joanna, Quinlan, Aoife, Ogier, Julien R., Darcy, Raphael, O'Driscoll, Caitriona M., Cryan, John F.

Journal:

Year:

2014

Language:

english

File:

PDF, 3.25 MB

english, 2014

14

Poly(ethylene glycol)-Based Peptidomimetic “PEGtide” of Oligo-Arginine Allows for Efficient siRNA Transfection and Gene Inhibition

Hibbitts, Alan, O’Connor, Aoife M., McCarthy, Joanna, Forde, Éanna B., Hessman, Gary, O’Driscoll, Caitriona M., Cryan, Sally-Ann, Devocelle, Marc

Journal:

Year:

2019

Language:

english

File:

PDF, 3.16 MB

english, 2019

15

Long-term stability of insulin glulisine loaded nanoparticles formulated using an amphiphilic cyclodextrin and designed for intestinal delivery

Presas, Elena, Sultan, Eric, Gervasi, Valeria, Crean, Abina M., Werner, Ulrich, Bazile, Didier, OâDriscoll, Caitriona M.

Journal:

Drug Development and Industrial Pharmacy

Year:

2020

File:

PDF, 1016 KB

2020

16

Bioavailability of lycopene in the rat: the role of intestinal lymphatic transport

Waleed Faisal, Caitriona M. O'Driscoll, Brendan T. Griffin

Journal:

Journal of Pharmacy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 215 KB

english, 2010

17

Amphiphilic polyallylamine based polymeric micelles for siRNA delivery to the gastrointestinal tract: In vitro investigations

Guo, Jianfeng, O’Mahony, Aoife M., Cheng, Woei Ping, O’Driscoll, Caitriona M.

Journal:

International Journal of Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 760 KB

english, 2013

18

Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments

O’Shea, Joseph P., Faisal, Waleed, Ruane-O’Hora, Therese, Devine, Ken J., Kostewicz, Edmund S., O’Driscoll, Caitriona M., Griffin, Brendan T.

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

19

Biomimetic gold nanocomplexes for gene knockdown: Will gold deliver dividends for small interfering RNA nanomedicines?

Guo, Jianfeng, Rahme, Kamil, Fitzgerald, Kathleen A., Holmes, Justin D., O’Driscoll, Caitriona M.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.45 MB

english, 2015

20

Conference Report: The 2nd Annual Irish Drug Delivery Network Conference with UK and Ireland Controlled Release Society: advancing drug delivery

Brayden, David J, Armstrong, Graham, O’Driscoll, Caitriona M

Journal:

Therapeutic Delivery

Year:

2010

Language:

english

File:

PDF, 1.47 MB

english, 2010

21

Gastrointestinal diseases and their impact on drug solubility: Celiac disease

Effinger, Angela, O'Driscoll, Caitriona M, McAllister, Mark, Fotaki, Nikoletta

Journal:

European Journal of Pharmaceutical Sciences

Year:

2020

File:

PDF, 1002 KB

2020

22

Gastrointestinal diseases and their impact on drug solubility: Ulcerative Colitis

Effinger, Angela, M O'Driscoll, Caitriona, McAllister, Mark, Fotaki, Nikoletta

Journal:

European Journal of Pharmaceutical Sciences

Year:

2020

File:

PDF, 1.90 MB

2020

23

Pattern recognition receptors—Molecular orchestrators of inflammation in inflammatory bowel disease

Walsh, David, McCarthy, Joanna, O’Driscoll, Caitriona, Melgar, Silvia

Journal:

Cytokine & Growth Factor Reviews

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

24

Biomimetic nanoparticles for siRNA delivery in the treatment of leukaemia

Guo, Jianfeng, Cahill, Mary R., McKenna, Sharon L., O'Driscoll, Caitriona M.

Journal:

Biotechnology Advances

Year:

2014

Language:

english

File:

PDF, 2.13 MB

english, 2014

25

Gold nanoparticles enlighten the future of cancer theranostics

Guo, Jianfeng, Rahme, Kamil, He, Yan, Li, Lin-Lin, Holmes, Justin, O'Driscoll, Caitriona

Journal:

International Journal of Nanomedicine

Year:

2017

Language:

english

File:

PDF, 1.00 MB

english, 2017

26

The potential for clinical translation of antibody-targeted nanoparticles in the treatment of acute myeloid leukaemia

Guo, Jianfeng, Luan, Xue, Cong, Zhongcheng, Sun, Yao, Wang, Limei, McKenna, Sharon L., Cahill, Mary R., O'Driscoll, Caitriona M.

Journal:

Journal of Controlled Release

Year:

2018

Language:

english

File:

PDF, 1001 KB

english, 2018

27

Pre-clinical evaluation of a modified cyclodextrin-based nanoparticle for intestinal delivery of Liraglutide

Presas, Elena, Tovar, Sulay, CuÃ±arro, Juan, OâShea, Joseph P., OâDriscoll, Caitriona M.

Journal:

Journal of Pharmaceutical Sciences

Year:

2020

File:

PDF, 1.65 MB

2020

28

Non-Viral Nanosystems for Gene and Small Interfering RNA Delivery to the Central Nervous System: Formulating the Solution

O'Mahony, Aoife M., Godinho, Bruno M. D. C., Cryan, John F., O'Driscoll, Caitriona M.

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 1.81 MB

english, 2013

29

The therapeutic and diagnostic potential of the prostate specific membrane antigen/glutamate carboxypeptidase II (PSMA/GCPII) in cancer and neurological disease

Evans, James C, Malhotra, Meenakshi, Cryan, John F., O'Driscoll, Caitriona M

Journal:

British Journal of Pharmacology

Year:

2016

Language:

english

File:

PDF, 2.27 MB

english, 2016

30

Micellar systems for oral drug delivery

Caitriona O'driscoll

Journal:

Journal of Pharmacy and Pharmacology

Year:

1998

Language:

english

File:

PDF, 76 KB

english, 1998

31

Nanoparticles and the Blood-Brain Barrier: Advancing fromIn-VitroModels Towards Therapeutic Significance

Mc Carthy, David J., Malhotra, Meenakshi, O’Mahony, Aoife M., Cryan, John F., O’Driscoll, Caitriona M.

Journal:

Pharmaceutical Research

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

32

Cell transfection with polycationic cyclodextrin vectors

Sally-Ann Cryan, Ann Holohan, Ruth Donohue, Raphael Darcy, Caitriona M O’Driscoll

Journal:

European Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 297 KB

english, 2004

33

7-formyl-10-methylisoellipticine, a novel ellipticine derivative, induces mitochondrial reactive oxygen species (ROS) and shows anti-leukaemic activity in mice

Russell, Eileen G., Guo, Jianfeng, O’Sullivan, Elaine C., O’Driscoll, Caitriona M., McCarthy, Florence O., Cotter, Thomas G.

Journal:

Investigational New Drugs

Year:

2016

Language:

english

File:

PDF, 905 KB

english, 2016

34

Scaffold‐based Delivery of Nucleic Acid Therapeutics for Enhanced Bone and Cartilage Repair

Kelly, Domhnall C, Raftery, Rosanne M, Curtin, Caroline M, O’Driscoll, Caitriona M, O’Brien, Fergal J

Journal:

Journal of Orthopaedic Research

Year:

2019

Language:

english

File:

PDF, 674 KB

english, 2019

35

A comparison of intestinal lymphatic transport and systemic bioavailability of saquinavir from three lipid-based formulations in the anaesthetised rat model

Brendan T. Griffin, Caitriona M. O'Driscoll

Journal:

Journal of Pharmacy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 168 KB

english, 2006

36

Therapeutic targeting in the silent era: advances in non-viral siRNA delivery

Guo, Jianfeng, Fisher, Karen A., Darcy, Raphael, Cryan, John F., O’Driscoll, Caitriona

Journal:

Molecular BioSystems

Year:

2010

Language:

english

File:

PDF, 1.86 MB

english, 2010

37

Pharmacokinetic, pharmacodynamic and biodistribution following oral administration of nanocarriers containing peptide and protein drugs

Griffin, Brendan T., Guo, Jianfeng, Presas, Elena, Donovan, Maria, Alonso, Maria J., O'Driscoll, Caitriona M.

Journal:

Advanced Drug Delivery Reviews

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

38

Anisamide-targeted PEGylated gold nanoparticles designed to target prostate cancer mediate: Enhanced systemic exposure of siRNA, tumour growth suppression and a synergistic therapeutic response in combination with paclitaxel in mice

Luan, Xue, Rahme, Kamil, Cong, Zhongcheng, Wang, Limei, Zou, Yifang, He, Yan, Yang, Hao, Holmes, Justin D., O'Driscoll, Caitriona M., Guo, Jianfeng

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2019

File:

PDF, 1.43 MB

2019

39

Oral delivery of non-viral nucleic acid-based therapeutics - do we have the guts for this?

O'Driscoll, Caitriona M., Bernkop-Schnürch, Andreas, Friedl, Julian D., Péat, Véronique, Jannin, Vincent

Journal:

European Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 1.15 MB

english, 2019

40

A click chemistry route to 2-functionalised PEGylated and cationic β-cyclodextrins: co-formulation opportunities for siRNA delivery

O'Mahony, Aoife M., Ogier, Julien, Desgranges, Stephane, Cryan, John F., Darcy, Raphael, O'Driscoll, Caitriona M.

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 479 KB

english, 2012

41

[Analytical Profiles of Drug Substances and Excipients] Volume 21 || Clofazimine

O'Driscoll, Caitriona M.

Year:

1992

Language:

english

File:

PDF, 1.17 MB

english, 1992

42

The effect of mixed micellar systems, bile salt/fatty acids, on the solubility and intestinal absorption of clofazimine (B663) in the anaesthetised rat

Joan R. O'Reilly, Owen I. Corrigan, Caitriona M. O'Driscoll

Journal:

International Journal of Pharmaceutics

Year:

1994

Language:

english

File:

PDF, 876 KB

english, 1994

43

Folate-targeted amphiphilic cyclodextrin nanoparticles incorporating a fusogenic peptide deliver therapeutic siRNA and inhibit the invasive capacity of 3D prostate cancer tumours

Evans, James C., Malhotra, Meenakshi, Sweeney, Katrina, Darcy, Raphael, Nelson, Colleen C., Hollier, Brett G., O’Driscoll, Caitriona M.

Journal:

International Journal of Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 912 KB

english, 2017

44

Cationic and PEGylated Amphiphilic Cyclodextrins: Co-Formulation Opportunities for Neuronal Sirna Delivery

O’Mahony, Aoife M., Ogier, Julien, Darcy, Raphael, Cryan, John F., O’Driscoll, Caitriona M., Antopolsky, Maxim

Journal:

Year:

2013

Language:

english

File:

PDF, 1.91 MB

english, 2013

45

Positively charged, surfactant-free gold nanoparticles for nucleic acid delivery

Guo, Jianfeng, Armstrong, Mark J., O'Driscoll, Caitriona M., Holmes, Justin D., Rahme, Kamil

Journal:

Year:

2015

Language:

english

File:

PDF, 3.06 MB

english, 2015

46

The use of collagen-based scaffolds to simulate prostate cancer bone metastases with potential for evaluating delivery of nanoparticulate gene therapeutics

Fitzgerald, Kathleen A., Guo, Jianfeng, Tierney, Erica G., Curtin, Caroline M., Malhotra, Meenakshi, Darcy, Raphael, O'Brien, Fergal J., O'Driscoll, Caitriona M.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.48 MB

english, 2015

47

Nanodelivery of immunogenic cell death-inducers for cancer immunotherapy

Sun, Dandan, Zhang, Jian, Wang, Limei, Yu, Zhuo, OâDriscoll, Caitriona M., Guo, Jianfeng

Journal:

Drug Discovery Today

Year:

2020

File:

PDF, 1.73 MB

2020

48

Formulation and evaluation of anisamide-targeted amphiphilic cyclodextrin nanoparticles to promote therapeutic gene silencing in a 3D prostate cancer bone metastases model

Evans, James C, Malhotra, Meenakshi, Fitzgerald, Kathleen A, Guo, Jianfeng, Cronin, Michael F, Curtin, Caroline M, O'Brien, Fergal J, Darcy, Raphael, O'Driscoll, Caitriona M

Journal:

Molecular Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 5.12 MB

english, 2016

49

Carcinoembryonic antigen (CEACAM) family members and Inflammatory Bowel Disease

Kelleher, Maebh, Singh, Raminder, O’Driscoll, Caitriona M., Melgar, Silvia

Journal:

Cytokine & Growth Factor Reviews

Year:

2019

Language:

english

File:

PDF, 2.59 MB

english, 2019

50

Gastrointestinal diseases and their impact on drug solubility: Crohn's disease

Effinger, Angela, O'Driscoll, Caitriona M, McAllister, Mark, Fotaki, Nikoletta

Journal:

European Journal of Pharmaceutical Sciences

Year:

2020

File:

PDF, 3.06 MB

2020

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